Question category: Gastroenterology
A 52 year old female presents with increasing fatigue over the last few months. She has also noticed pains in the joints of his fingers. She has noticed she is irritable and is having severe mood swings. Recently her periods have stopped. She has also noticed being thirsty and increased urinary frequency. On examination she appears very tanned and there is evidence of hepatomegaly. Given the most likely diagnosis, what is most useful for monitoring response to treatment?