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Question category: Rheumatology

A 54 year old lady presents with joint pains. She gives a history of Raynaud’s syndrome and GI upset with diarrhoea and difficulty swallowing with some weight loss. She has some telangiectasia evident on her face. Bloods reveal a normochromic normocytic anaemia and positive anticentromere pattern. Which of the following is the most likely diagnosis?

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