Question category: Rheumatology
A 50 year old with obesity and hypertension present with pain and swelling in his left first MTP. On examination there is evidence of swelling and erythema over his first MTP. He is currently on Bendroflumethiazide, amlodipine and ramipril for his hypertension and also aspirin and orlistat. There is nil else of note on examination. An x-ray of his left foot shows reduced join space and calcification. Which drug could be causative?