ReviseMRCP

Question category: Endocrinology

How does the PPARgamma agonist, pioglitazone cause its effects?

Activate G linked proteins and upregulate genes

Heterodimer formation with the retinoid X receptor which binds to a promoter region and downregulates transcription of genes

Heterodimer formation with the retinoid X receptor which binds to a promoter region and upregulates transcription of genes

Activate G linked proteins and down regulate genes.

Reduce peripheral resistance

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