Question category: Endocrinology
A 64 year old gentleman with type 2 diabetes mellitus is found to have pre-proliferative retinopathy on his annual screening. He is obese and his blood pressure is 155/90 mmHg. He has evidence of proteinuria on urinalysis. A recent HBA1c is 8.0%. Which of the following would be most useful for reducing the progression of both the retinopathy and proteinuria?